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- Endoscopy and Biopsy
- • A biopsy is necessary for a definitive diagnosis and is most useful for patients with suspected metastatic
- disease. The primary tumor may be biopsied surgically or with a CT- or ultrasound-directed needle biopsy or
- surgically after a metabolic work-up reveals it is not a pheochromocytoma. Biopsies of suspected
- pheochromocytoma must not be undertaken without full catecholamine blockade (see below).
- • Alternatively, an accessible metastasis in the lymph nodes or liver can be biopsied.